Epilepsy Bio

The EpilepCell™ (aka JadiCell™) is unique in that it possesses features of mesenchymal stem cells, however, EpilepCells outperform these cells in terms of a) enhanced growth factor production; b) augmented ability to secrete exosomes; and c) superior angiogenic
and neurogenic ability.

According to the National Institutes of Health (NIH), Epilepsy is a chronic brain disorder in which groups of nerve cells, or neurons, in the brain sometimes send the wrong signals and cause seizures. Neurons normally generate electrical and chemical signals that act on other neurons, organs, and muscles to produce human thoughts, feelings, and actions.

During a seizure, many neurons send signals at the same time, much faster than normal. This surge of excessive electrical activity may cause involuntary movements, sensations, emotions, and/or behaviors. The disturbance of normal nerve cell activity may cause a loss of awareness. Some people recover immediately after a seizure, while others may take minutes to hours to feel like themselves again. During this time, they may feel tired, sleepy, weak, or confused.

Epilepsy (sometimes referred to as a seizure disorder) can have many different causes and seizure types. Epilepsy varies in severity and impact from person to person and can be accompanied by a range of co-existing conditions. Epilepsy is sometimes called “the epilepsies” because of the diversity of types and causes. Some people may have convulsions (muscles contract repeatedly) and lose consciousness. Others may simply stop what they are doing, have a brief lapse of awareness, and stare into space for a short period. Some people have seizures very infrequently, while other people may experience hundreds of seizures each day.

While any seizure is cause for concern, having a seizure does not by itself mean a person has epilepsy. First seizures, febrile seizures, nonepileptic events, and eclampsia (a life-threatening condition that can occur during pregnancy) are examples of conditions involving seizures that may not be associated with epilepsy. Regardless of the type of seizure, it’s important to inform your doctor when you have a seizure.

Anyone can develop epilepsy. It affects both men and women of all races, ethnic backgrounds, and ages.

Epilepsy has many possible causes, but about half of people living with epilepsy do not know the cause. In some cases, epilepsy is clearly linked to genetic factors, developmental brain abnormalities, infection, traumatic brain injury (TBI), stroke, brain tumors, or other identifiable problems. Anything that disturbs the normal pattern of nerve cell activity—from illness to brain damage to brain development problems—can lead to seizures.

Epilepsy may develop because of problems in the brain’s wiring, an imbalance of nerve signaling in the brain (in which some cells are unusually active or stop other brain cells from sending messages), or some combination of these factors. Sometimes, when the brain tries to repair itself after a head injury, stroke, or other problem, it can unintentionally create nerve connection issues that lead to seizures.

Diagnosing Epilepsy

Accurate diagnosis of epilepsy is crucial for finding an effective treatment. Several tests are used to determine whether a person has epilepsy and, if so, what kind of seizures the person has. Generally, epilepsy is diagnosed after a person has had two or more unprovoked seizures separated by at least 24 hours.

Medical history
Taking a detailed medical history, including symptoms and duration of the seizures, is still one of the best methods available to determine what kind of seizures a person has had and to help determine what type of epilepsy the person has. The medical history should include details about any past illnesses or other symptoms a person may have had, as well as any family history of seizures.

Since people who have a seizure often do not remember what happened, accounts from people who have witnessed the seizures are very important. The person who experienced the seizure is asked about whether they felt anything unique (warning experiences) before the seizure started. The observers will be asked to provide a detailed description and timeline for the seizure.

Treating epilepsy and seizures
Once epilepsy is diagnosed, it is important to begin treatment as soon as possible. There are many different ways to successfully control seizures. There are several treatment approaches that can be used, depending on the individual and the type of epilepsy.