{"id":95,"date":"2024-01-09T12:05:15","date_gmt":"2024-01-09T12:05:15","guid":{"rendered":"https:\/\/alsbiologics.com\/?page_id=95"},"modified":"2024-01-16T12:25:31","modified_gmt":"2024-01-16T12:25:31","slug":"epilepcells","status":"publish","type":"page","link":"https:\/\/epilepsybio.com\/index.php\/epilepcells\/","title":{"rendered":"EpilepCells"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Header&#8221; _builder_version=&#8221;4.22.1&#8243; background_color=&#8221;#0C71C3&#8243; background_enable_image=&#8221;off&#8221; custom_padding=&#8221;8vw||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.22.1&#8243; background_enable_image=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;||||||||&#8221; header_font=&#8221;Glegoo|700|||||||&#8221; header_font_size=&#8221;80px&#8221; header_line_height=&#8221;1.3em&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;150deg&#8221; background_color_gradient_stops=&#8221;rgba(0,174,255,0.16) 0%|rgba(29,72,192,0) 100%&#8221; background_color_gradient_start=&#8221;rgba(0,174,255,0.16)&#8221; background_color_gradient_end=&#8221;rgba(29,72,192,0)&#8221; text_orientation=&#8221;right&#8221; background_layout=&#8221;dark&#8221; custom_padding=&#8221;70px|70px|70px|70px|true|true&#8221; custom_padding_tablet=&#8221;40px|40px|40px|40px|true|true&#8221; custom_padding_phone=&#8221;20px|20px|20px|20px|true|true&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; animation_style=&#8221;flip&#8221; header_font_size_tablet=&#8221;50px&#8221; header_font_size_phone=&#8221;30px&#8221; header_font_size_last_edited=&#8221;on|phone&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_vertical=&#8221;40px&#8221; box_shadow_blur=&#8221;200px&#8221; box_shadow_spread=&#8221;-10px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1>Epilepsy Bio<\/h1>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;20vw|||&#8221; custom_padding_tablet=&#8221;20px|||&#8221; custom_padding_phone=&#8221;20px|||&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; padding_tablet=&#8221;20px|||&#8221; padding_last_edited=&#8221;on|phone&#8221; custom_padding__hover=&#8221;|||&#8221; padding_phone=&#8221;20px|||&#8221;][et_pb_text _builder_version=&#8221;4.22.1&#8243; text_font=&#8221;|600|||||||&#8221; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;1.9em&#8221; background_layout=&#8221;dark&#8221; text_font_size_tablet=&#8221;&#8221; text_font_size_phone=&#8221;14px&#8221; text_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: large;\">The EpilepCell\u2122 (aka JadiCell\u2122) is unique in that it possesses features of mesenchymal stem cells, however, EpilepCells outperform these cells in terms of a) enhanced growth factor production; b) augmented ability to secrete exosomes; and c) superior angiogenic <br \/>and neurogenic ability.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.22.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.22.1&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-2px|auto||auto||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.22.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.22.1&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-59px|||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p><span style=\"color: #000000; font-size: large;\"><strong>EpilepCells<br \/><\/strong><\/span><\/p>\n<p><span style=\"font-size: large;\"><strong><span style=\"color: #000000;\">Mesenchymal Stem Cell Therapy of Epilepsy and Seizure Disorders<\/span><\/strong><\/span><br \/><span style=\"color: #000000; font-size: large;\"><strong>Application No.: 63\/41886<\/strong><\/span><\/p>\n<p><span style=\"color: #000000; font-size: large;\">Disclosed are novel compositions of matter and treatment methods for reducing and\/or reversing epilepsy through administration of mesenchymal stem cells in order to induce immune modulation and\/or regenerative processes. In one embodiment umbilical cord mesenchymal stem cells are administered to a patient suffering from epilepsy at a concentration and frequency sufficient to inhibit neuronal hyperactivation and\/or reduce neuroinflammatory status of the patient<\/span><\/p>\n<p><span style=\"color: #000000; font-size: large;\">Temporal lobe epilepsy (TLE) is a chronic disease characterized by spontaneous, progressive seizures. In many patients, TLE is initiated by brain injury, strokes, tumors or status epilepticus (SE), which is often followed by a latency period of 5\u201310 years before the onset of spontaneous recurrent motor seizure (SRMS). SE is defined as a continuous seizure activity lasting more than 5 min. SRMS is the repeated unprovoked seizures that occurs in the chronic phase of epilepsy. The main physiopathological findings observed in TLE are neuronal loss, reactive gliosis, aberrant mossy fiber sprouting and spontaneous recurrent motor seizure (SRMS). Antiepileptic drugs fail to well-control seizures in approximately 30% of epilepsy patients.<\/span><br \/><span style=\"color: #000000; font-size: large;\"><\/span><\/p>\n<p><span style=\"color: #000000; font-size: large;\">There is a significant need in the field to develop means of controlling seizures and\/or reversing epilepsy.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Epilepsy BioThe EpilepCell\u2122 (aka JadiCell\u2122) is unique in that it possesses features of mesenchymal stem cells, however, EpilepCells outperform these cells in terms of a) enhanced growth factor production; b) augmented ability to secrete exosomes; and c) superior angiogenic and neurogenic ability.EpilepCells Mesenchymal Stem Cell Therapy of Epilepsy and Seizure DisordersApplication No.: 63\/41886 Disclosed are [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-95","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/epilepsybio.com\/index.php\/wp-json\/wp\/v2\/pages\/95","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/epilepsybio.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/epilepsybio.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/epilepsybio.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/epilepsybio.com\/index.php\/wp-json\/wp\/v2\/comments?post=95"}],"version-history":[{"count":17,"href":"https:\/\/epilepsybio.com\/index.php\/wp-json\/wp\/v2\/pages\/95\/revisions"}],"predecessor-version":[{"id":172,"href":"https:\/\/epilepsybio.com\/index.php\/wp-json\/wp\/v2\/pages\/95\/revisions\/172"}],"wp:attachment":[{"href":"https:\/\/epilepsybio.com\/index.php\/wp-json\/wp\/v2\/media?parent=95"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}